Target validation · Research update
Uncertainty-aware drug-target interaction prediction
Quantifying evidential uncertainty helps rank DTIs, reduce false positives and focus experimental validation.
Nature Communications
EviDTI ranks candidate drug-target interactions with uncertainty quantification and evaluates generalization on an external test set.
Projects should retain training-data boundaries, independent test sets, confidence thresholds and experimental review records.
Read source articleDOI: 10.1038/s41467-025-62235-6